WHY UTILIZE MOLECULAR TESTING?

   - Rapid diagnosis
   - Cost effective
   - Highly specific
   - Improved patient care
  -  Provides ultimate resolution
   - Outside interference from medication or treatments does not alter 
     the test results

Competitive PCR to determine bcr/abl levels in a patient with CML



Real Time PCR



Analysis of B cell gene rearrangement showing clonality


Analysis of factor II for the 20210A mutation


DNA Sequence Analysis


DNA sequencing reveals a P53 mutation


T Cell Receptor & Analysis

MOLECULAR PATHOLOGY CONSULTANT:

John W. Longshore, Ph.D., F.A.C.M.G.

   Dr. Longshore received his undergraduate training at Georgia Tech
   and his doctoral degree in medical genetics from the University of
   Alabama at Birmingham. His fellowship at Greenwood Genetic 
   Center in South Carolina included research on the fragile X and 
   FRAXE syndromes. Dr. Longshore serves as the Director of 
   Molecular Pathology for Carolinas Laboratory Network. He is a 
   Diplomate of the American Board of Medical Genetics in Clinical 
   Molecular Genetics.